SCHEMBL14490239

SCHEMBL14490239

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=CC=Cc3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.56
NFE2L2 Q16236 2/20 0.46
RELA Q04206 1/20 0.43
CA1 P00915 1/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 2/20 0.42
CYP2A6 P11509 1/20 0.41
FBP1 P09467 1/20 0.41
ALOX5 P09917 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14490262 1.00 APP (0.56) APPNFE2L2RELACA1ALDH1A1
SCHEMBL13049996 1.00 APP (0.56) APPNFE2L2RELACA1ALDH1A1
SCHEMBL18680252 1.00 APP (0.56) APPNFE2L2RELACA1ALDH1A1
SCHEMBL18294660 0.94 APP (0.50) APPNFE2L2RELACA1ALDH1A1
SCHEMBL10424926 0.92 MAOB (0.54) APPNFE2L2RELAALDH1A1MAPT
SCHEMBL2622626 0.92 MAOB (0.54) APPNFE2L2RELAALDH1A1MAPT
SCHEMBL14727250 0.92 MAOB (0.54) APPNFE2L2RELAALDH1A1MAPT
SCHEMBL13049995 0.92 TRPM8 (0.51) APPNFE2L2RELAALDH1A1MAPT
SCHEMBL13049997 0.92 MAOB (0.54) APPNFE2L2RELAALDH1A1MAPT
SCHEMBL75905 0.91 NFE2L2 (0.56) APPNFE2L2RELACA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070141388-A1 Electroluminescent device containing a butadiene derivative EASTMAN KODAK COMPANY 2007-06-21 US disclosed
US-20070141388-A1 Electroluminescent device containing a butadiene derivative EASTMAN KODAK COMPANY 2007-06-21 US disclosed