SCHEMBL1449047

SCHEMBL1449047

O=C(O)c1ccccc1SC(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.61
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA4 P22748 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CYP1A2 P05177 1/20 0.52
ALDH1A1 P00352 5/20 0.50
ALOX15 P16050 1/20 0.50
KCNK2 O95069 1/20 0.50
KCNK10 P57789 1/20 0.50
HTT P42858 3/20 0.47
HPGD P15428 2/20 0.47
PKM P14618 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
FFAR4 Q5NUL3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11031893 0.86 ALDH1A1 (0.45) POLBCA12CA1CA2CA4
SCHEMBL31319419 0.85 POLB (0.47) POLBCA12CA1CA2CA4
SCHEMBL27051667 0.83 ALB (0.52) POLBCA12CA1CA2CA4
SCHEMBL1448528 0.82 ALDH1A1 (0.48) POLBCA12CA1CA2CA4
SCHEMBL149060 0.82 SIRT1 (0.55) POLBALDH1A1KCNK2KCNK10HTT
SCHEMBL7823647 0.81 KCNK2 (0.43) POLBCA12CA1CA2CA4
SCHEMBL27760461 0.80 POLB (0.61) POLBCA12CA1CA2CA4
SCHEMBL10447747 0.80 POLB (0.61) POLBCA12CA1CA2CA4
SCHEMBL27051708 0.79 POLB (0.42) POLBCA12CA1CA2CA4
SCHEMBL2468600 0.78 POLB (0.59) POLBCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119486565-A Perovskite precursor solution, perovskite solar cell, preparation method and photovoltaic module 天合光能股份有限公司 2025-02-18 CN claimed
CN-106750655-A A kind of anti-slip rubber sole 福建省惠安县万事达鞋塑有限公司 2017-05-31 CN claimed
CN-119486565-A Perovskite precursor solution, perovskite solar cell, preparation method and photovoltaic module 天合光能股份有限公司 2025-02-18 CN disclosed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
WO-2023102162-A1 TGONOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF TANGO THERAPEUTICS, INC. (US) 2023-06-08 WO disclosed
WO-2023078252-A1 PPARG INVERSE AGONISTS AND USES THEREOF FLARE THERAPEUTICS INC. (US) 2023-05-11 WO disclosed
WO-2023021498-A1 FUSED AZOLE AND FURAN BASED NUCLEOSIDE ANALOGS AND USES THEREOF MOYA BIO LTD. (IL) 2023-02-23 WO disclosed
EP-4065577-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-10-05 EP disclosed
EP-3006429-B1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL CO (JP) 2019-02-06 EP disclosed
CN-106750655-A A kind of anti-slip rubber sole 福建省惠安县万事达鞋塑有限公司 2017-05-31 CN disclosed
EP-2655337-B1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed
EP-2655337-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF Sumitomo Chemical Company Limited (JP) 2013-10-30 EP disclosed
WO-2012086848-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-28 WO disclosed
US-8183253-B2 Condensing (3-trifluoromethylsulfonyl) benzoyl chloride and 4-methyl-2-nitro-aniline; reducing nitro group with stannous chloride; condensing amino group with cyanamide; cyclocondensing guanidine group with 3-dimethylamino-1-pyridin-3-yl-propenone; antiproliferative agents; chronic myeloid leukemia NATCO PHARMA LIMITED (IN) 2012-05-22 US disclosed
US-7910598-B2 Condensing (3-trifluoromethylsulfonyl) benzoyl chloride and 4-methyl-2-nitro-aniline; reducing nitro group with stannous chloride; condensing amino group with cyanamide; cyclocondensing guanidine group with 3-dimethylamino-1-pyridin-3-yl-propenone; antiproliferative agents NATCO PHARMA LIMITED (IN) 2011-03-22 US disclosed
US-20080306100-A1 PHENYLAMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF BCR-ABL KINASE NATCO PHARMA LIMITED (IN) 2008-12-11 US disclosed
US-20070232633-A1 Novel phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase NATCO PHARMA LIMITED (IN) 2007-10-04 US disclosed
US-4020169-A FROM ARYL IODIDE OR BROMIDE AND TRIFLUOROMETHYL THIO COPPER MERCK & CO., INC. (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 POLB 4715/4885CA12 3418/4885CA1 2842/4885
US-20070232633-A1 Novel phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase ABL1, ABL2, BCR POLB 1826/4885CA12 4882/4885CA1 4872/4885
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 POLB 1145/4885CA12 2389/4885CA1 2206/4885
US-20080306100-A1 PHENYLAMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF BCR-ABL KINASE ABL1, ABL2, BCR POLB 2779/4885CA12 4745/4885CA1 4604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.