SCHEMBL14493191

SCHEMBL14493191

C=Cc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TSHR P16473 1/20 0.48
KMT2A Q03164 6/20 0.45
RAD51 Q06609 1/20 0.45
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
PPARG P37231 1/20 0.42
NCOA2 Q15596 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
TGM2 P21980 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 2/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EGFR P00533 1/20 0.40
ERBB2 P04626 1/20 0.40
SRD5A2 P31213 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2791741 0.92 ALDH1A1 (0.50) ALDH1A1TSHRKMT2AMAPTRAB9A
Butadiene SCHEMBL896449 0.84 TDP1 (0.45) ALDH1A1KMT2ARAD51MAPTPPARG
SCHEMBL1624304 0.83 KMT2A (0.52) ALDH1A1KMT2AMAPTPPARGNCOA2
SCHEMBL16652556 0.82 ALDH1A1 (0.38) ALDH1A1TSHRKMT2ARAD51MAPT
SCHEMBL6885150 0.82 KMT2A (0.50) ALDH1A1KMT2ATGM2L3MBTL1MEN1
Acrylic Acid SCHEMBL6692818 0.82 THRB (0.46) ALDH1A1KMT2ARAD51MAPTPPARG
SCHEMBL3903145 0.82 ALDH1A1 (0.48) ALDH1A1TSHRKMT2ARAD51MAPT
Styrene SCHEMBL7954200 0.81 ELANE (0.58) ALDH1A1TSHRKMT2AMAPTRAB9A
SCHEMBL5200353 0.81 MAPT (0.57) ALDH1A1TSHRKMT2AMAPTRAB9A
SCHEMBL1143616 0.81 KMT2A (0.66) ALDH1A1KMT2AMAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229836-B2 Polymers for binding of phenols THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 2007-06-12 US disclosed