SCHEMBL14494

SCHEMBL14494

CC(C)(C)OC(=O)N1CC[C@@H](O)C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.53
CHRM2 P08172 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
RECQL P46063 1/20 0.50
EPHX1 P07099 1/20 0.50
USP2 O75604 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GPR119 Q8TDV5 3/20 0.47
NR1H2 P55055 1/20 0.46
KDM4E B2RXH2 1/20 0.46
THRB P10828 1/20 0.46
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
USP30 Q70CQ3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241055 1.00 HPGD (0.53) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL14431 1.00 HPGD (0.53) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL29433963 0.98 HPGD (0.51) HPGDCHRM2CHRM1CHRM3RECQL
Hydroxyamine SCHEMBL28087664 0.96 HPGD (0.50) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL3530704 0.92 EPHX1 (0.48) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL1068107 0.89 MEN1 (0.56) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL30862413 0.89 MEN1 (0.56) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL190483 0.89 MEN1 (0.56) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL215146 0.89 MEN1 (0.56) HPGDCHRM2CHRM1CHRM3RECQL
SCHEMBL28126430 0.89 HPGD (0.44) HPGDCHRM2CHRM1CHRM3RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2414 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080664-A Preparation method of Fu Kasai ethyl acetate 南京康立瑞生物科技有限公司 2024-12-06 CN claimed
CN-119039201-A Synthesis method of (S) -1-tert-butoxycarbonyl-3-aminopyrrolidine 苏州汉德创宏生化科技有限公司 2024-11-29 CN claimed
CN-118405996-A Preparation method of Epimer Fu Kasai 仁合益康集团有限公司 2024-07-30 CN claimed
CN-118290424-A Preparation method of aminopyrimidino pyrazole/pyrrole derivative based on double decomposition reaction 四川大学华西医院 2024-07-05 CN claimed
CN-118255703-A Preparation method of estrogen receptor degradation agent 南京医科大学 2024-06-28 CN claimed
CN-112209865-A Production method of (R) - (-) -N-Boc-3-pyrrolidinol 中山澳达特罗生物科技有限公司 2021-01-12 CN claimed
CN-106084567-A A kind of mine cable protective cover material 安徽光复电缆有限公司 2016-11-09 CN claimed
CN-105985573-A Polyethylene insulation control cable 安徽德源电缆集团有限公司 2016-10-05 CN claimed
CN-105646321-A Preparation method of (S)-3-hydroxypyrrolidine hydrochloride 中国药科大学 2016-06-08 CN claimed
US-8975262-B2 Synthetic mimetics of host defense and uses thereof CELLCEUTIX CORPORATION (US) 2015-03-10 US claimed
CN-102256614-B Synthetic mimetics of host defense and uses thereof POLYMEDIX INC 2014-01-08 CN claimed
US-20130090345-A1 Synthetic Mimetics Of Host Defense And Uses Thereof POLYMEDIX, INC. (US) 2013-04-11 US claimed
US-8278309-B2 Synthetic mimetics of host defense and uses thereof POLYMEDIX, INC. (US) 2012-10-02 US claimed
CN-102256614-A Synthetic mimetics of host defense and uses thereof POLYMEDIX INC 2011-11-23 CN claimed
EP-2358380-A1 SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF Polymedix, Inc. (US) 2011-08-24 EP claimed
WO-2010062573-A1 SYNTHETIC MIMETICS OF HOST DEFENSE AND USES THEREOF POLYMEDIX, INC. (US) 2010-06-03 WO claimed
US-20100105703-A1 Synthetic Mimetics Of Host Defense And Uses Thereof POLYMEDIX, INC. (US) 2010-04-29 US claimed
CN-122079984-A FGFR3 inhibitor compounds 2026-05-26 CN disclosed
US-4771046-A ANTIBIOTICS SANKYO COMPANY, LIMITED (JP) 1988-09-13 US disclosed
EP-0202048-A1 Carbapenem derivatives, their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1986-11-20 EP disclosed