Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431 | 1.00 | HPGD (0.53) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL14494 | 1.00 | HPGD (0.53) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL29433963 | 0.98 | HPGD (0.51) | HPGDCHRM2CHRM1CHRM3RECQL | |
| Hydroxyamine SCHEMBL28087664 | 0.96 | HPGD (0.50) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL3530704 | 0.92 | EPHX1 (0.48) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL1068107 | 0.89 | MEN1 (0.56) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL30862413 | 0.89 | MEN1 (0.56) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL190483 | 0.89 | MEN1 (0.56) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL215146 | 0.89 | MEN1 (0.56) | HPGDCHRM2CHRM1CHRM3RECQL | |
| SCHEMBL28126430 | 0.89 | HPGD (0.44) | HPGDCHRM2CHRM1CHRM3RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236766-A1 | POLYURETHANE FOR USE IN POLISHING LAYER, POLISHING LAYER, POLISHING PAD, AND METHOD FOR MODIFYING POLISHING LAYER | KURARAY CO., LTD. (JP) | 2025-07-24 | — | — | US | claimed |
| CN-114667167-B | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-118791425-A | Synthesis method of 1-BOC-3-piperidone and similar cyclic ketone compounds thereof | 浙江尚科生物医药有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118290424-A | Preparation method of aminopyrimidino pyrazole/pyrrole derivative based on double decomposition reaction | 四川大学华西医院 | 2024-07-05 | — | — | CN | claimed |
| CN-118255703-A | Preparation method of estrogen receptor degradation agent | 南京医科大学 | 2024-06-28 | — | — | CN | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| CN-115572297-B | Pyrazolopyrimidine-containing o-phenylenediamine derivative, and preparation method and application thereof | 山东大学 | 2024-04-26 | — | — | CN | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| CN-112839985-B | Polyurethane for polishing layer, polishing pad, and method for modifying polishing layer | 株式会社可乐丽 | 2023-10-20 | — | — | CN | claimed |
| WO-2005051917-A9 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2005-09-29 | — | — | WO | claimed |
| US-20050165005-A1 | Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2005-07-28 | — | — | US | claimed |
| WO-2005051917-A1 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA S.A. (FR) | 2005-06-09 | — | — | WO | claimed |
| EP-1131460-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXY-PYRROLIDINE DERIVATIVEES BY ENZYMATIC HYDROXYLATION | EIDGENOESS TECH HOCHSCHULE (CH) | 2004-10-06 | — | — | EP | claimed |
| US-20040029237-A1 | Process for preparing n-substituted 4-hydroxypiperidines by enzymatic hudroxylation | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2004-02-12 | — | — | US | claimed |
| US-20030219883-A1 | Process for preparing optically active 3-hydroxypyrrolidine derivatives by enzymatic hydroxylation | LI ZHI (CH) | 2003-11-27 | — | — | US | claimed |
| US-20020106763-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXY-PYRROLIDINE DERIVATIVES BY ENZYMATIC HYDROXYLATION | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2002-08-08 | — | — | US | claimed |
| EP-1188837-A1 | Process for preparing N-substituted 4-hydroxypiperidines by enzymatic hydroxylation | Eidgenössische Technische Hochschule Zürich (CH) | 2002-03-20 | — | — | EP | claimed |
| EP-1131460-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXY-PYRROLIDINE DERIVATIVEES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029606-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE-3-HYDROXY-PYRROLIDINE DERIVATIVES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2000-05-25 | — | — | WO | claimed |