SCHEMBL215146

SCHEMBL215146

CC(C)(C)OC(=O)N1CCC[C@@H](O)C1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPT P10636 1/20 0.56
KMT2A Q03164 1/20 0.56
HPGD P15428 1/20 0.54
EPHX1 P07099 1/20 0.48
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
USP2 O75604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PREP P48147 2/20 0.46
USP30 Q70CQ3 1/20 0.44
RECQL P46063 1/20 0.44
NR1H2 P55055 1/20 0.44
HSD17B10 Q99714 1/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30862413 1.00 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL190483 1.00 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL1068107 1.00 MEN1 (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
Water SCHEMBL28231929 0.98 MEN1 (0.58) MEN1ALDH1A1MAPTKMT2AHPGD
Water SCHEMBL28231930 0.98 MEN1 (0.58) MEN1ALDH1A1MAPTKMT2AHPGD
Ammonia Solution, Strong SCHEMBL28243999 0.98 MEN1 (0.55) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL24438917 0.95 HPGD (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL22439376 0.95 HPGD (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL2820898 0.95 HPGD (0.56) MEN1ALDH1A1MAPTKMT2AHPGD
Alcohol SCHEMBL4274896 0.94 MEN1 (0.54) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791425-A Synthesis method of 1-BOC-3-piperidone and similar cyclic ketone compounds thereof 浙江尚科生物医药有限公司 2024-10-18 CN claimed
CN-118272334-A Carbonyl reductase mutant and application thereof in synthesis of (R) -N-Boc-3-hydroxy piperidine 西南大学 2024-07-02 CN claimed
EP-3115358-A1 METHOD OF PREPARATION AND CHIRAL INVERSION OF CHIRAL-1-T-BUTOXYCARBONYL-3-HYDROXY PIPERIDINE ABA Chemicals Corporation (CN) 2017-01-11 EP claimed
CN-106188062-A Replace the preparation method of Buddhist nun according to Shandong, replace intermediate and the preparation method of intermediate of Buddhist nun according to Shandong 苏州鹏旭医药科技有限公司 2016-12-07 CN claimed
CN-103864673-B The method of the preparation of chirality-1-tertbutyloxycarbonyl-3-hydroxy piperidine and chirality upset ABA CHEMICALS CORPORATION (CN) 2016-03-23 CN claimed
CN-103864673-A Preparation of chirality-1-t-butyloxycarboryl-3-hydroxy piperidine and method for chirality turning ABA CHEMICALS CORP 2014-06-18 CN claimed
US-8697711-B2 Inhibitors of bruton'S tyrosine kinase PHARMACYCLICS, INC. (US) 2014-04-15 US claimed
CN-103571908-A Method for preparing chiral N-tert-butyloxycarboryl-3-hydroxypiperidine SYNCOZYMES SHANGHAI CO LTD 2014-02-12 CN claimed
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof LG CHEM, LTD. (KR) 2026-05-26 US disclosed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
US-12630562-B2 Piperidylurea compounds and methods of use thereof ARCUS BIOSCIENCES, INC. (US) 2026-05-19 US disclosed
WO-2026098672-A1 BIAZACYCLOALKANE MENIN-MLL PROTEIN INHIBITORS, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 赛诺哈勃药业(成都)有限公司 2026-05-15 WO disclosed
CN-122010910-A Biazacycloalkane Menin-MLL protein inhibitor, pharmaceutical composition and application thereof 赛诺哈勃药业(成都)有限公司 2026-05-12 CN disclosed
US-20260103461-A1 ESTROGEN RECEPTOR MODULATORS AND USES THEREOF OLEMA PHARMACEUTICALS INC (US) 2026-04-16 US disclosed
EP-0900218-A1 HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1999-03-10 EP disclosed
EP-0497303-B1 Carbamic acid derivatives and method for preparing the same KYORIN SEIYAKU KK (JP) 1998-05-27 EP disclosed
WO-1997040044-A1 HETEROCYCLIC COMPOUNDS ELI LILLY AND COMPANY (US) 1997-10-30 WO disclosed
US-5300515-A Cognition activators for brain disorders; alzheimer*s disease KYORIN PHARMACEUTICAL CO., LTD. (JP) 1994-04-05 US disclosed
CN-1064075-A Carbamic acid derivative and preparation method thereof ANZURIN PHARMACEUTICAL CO LTD (JP) 1992-09-02 CN disclosed
EP-0497303-A2 Carbamic acid derivatives and method for preparing the same KYORIN PHARMACEUTICAL CO., LTD. (JP) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103461-A1 ESTROGEN RECEPTOR MODULATORS AND USES THEREOF ESRRA, GPER1, ESR2 MEN1 4532/4885ALDH1A1 1137/4885MAPT 4756/4885
US-12630562-B2 Piperidylurea compounds and methods of use thereof CLIC1, HCCS, CNR1 MEN1 2043/4885ALDH1A1 1002/4885MAPT 4783/4885
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof DGAT2, DGAT1, SOAT2 MEN1 4788/4885ALDH1A1 597/4885MAPT 4476/4885
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof DGAT2, DGAT1, DLAT MEN1 4822/4885ALDH1A1 885/4885MAPT 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.