Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.74 |
| ▸ | MAP3K9 | P80192 | 7/20 | 0.72 |
| ▸ | MAP3K11 | Q16584 | 7/20 | 0.72 |
| ▸ | PRKCA | P17252 | 4/20 | 0.72 |
| ▸ | MAP3K10 | Q02779 | 3/20 | 0.72 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.72 |
| ▸ | PRKCG | P05129 | 2/20 | 0.72 |
| ▸ | PRKCB | P05771 | 2/20 | 0.72 |
| ▸ | PRKCH | P24723 | 2/20 | 0.72 |
| ▸ | PRKCI | P41743 | 2/20 | 0.72 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.72 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.72 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.72 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494156 | 0.86 | KDR (0.79) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14494158 | 0.85 | KDR (1.00) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL3268039 | 0.85 | MAP3K9 (0.76) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL3072275 | 0.84 | MAP3K11 (1.00) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL3268623 | 0.83 | MAP3K9 (0.73) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14510328 | 0.83 | KDR (0.67) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14494163 | 0.82 | MAP3K9 (0.69) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14494184 | 0.82 | MAP3K9 (0.72) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14494166 | 0.79 | KDR (0.69) | KDRMAP3K9MAP3K11PRKCAMAP3K10 | |
| SCHEMBL14494159 | 0.76 | KDR (0.90) | KDRPDGFRBKITFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230026-B2 | Administering fused pyrrolocarbazole compound for therapy of prostate disorders | CEPHALON, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| US-7230026-B2 | Administering fused pyrrolocarbazole compound for therapy of prostate disorders | CEPHALON, INC. (US) | 2007-06-12 | — | — | US | disclosed |