Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021890 | 0.97 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 | |
| SCHEMBL1021889 | 0.93 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8383162 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 | |
| SCHEMBL8383160 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 | |
| SCHEMBL10008035 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL9055054 | 0.78 | MEN1 (0.61) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5739701 | 0.77 | ADORA2A (0.60) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 | |
| Hydrochloric Acid SCHEMBL5965726 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3716740 | 0.76 | ALDH1A1 (0.93) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 | |
| SCHEMBL7829113 | 0.76 | ALDH1A1 (0.93) | ALDH1A1MEN1KMT2AMT-CO2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910578-B2 | 8,10-diaza-bicyclo[4.3.1]decane derivatives and their medical use | NEUROSEARCH A/S (DK) | 2011-03-22 | — | — | US | disclosed |
| US-20090099153-A1 | NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE | ANIONA APS (DK) | 2009-04-16 | — | — | US | disclosed |
| EP-2029607-A1 | NOVEL 8,10-DIAZA-BICYCLOÝ4.3.1¨DECANE DERIVATIVES AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007135121-A1 | NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099153-A1 | NOVEL 8,10-DIAZA-BICYCLO[4.3.1]DECANE DERIVATIVES AND THEIR MEDICAL USE | CHRNA10, CHRNA7, CHRNA3 | ALDH1A1 1167/4885MEN1 3963/4885KMT2A 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.