SCHEMBL1449481

SCHEMBL1449481

O=C(Cc1ccco1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
MAPK1 P28482 2/20 0.48
HPGD P15428 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
CES1 P23141 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
POLB P06746 2/20 0.48
RECQL P46063 1/20 0.48
ESR2 Q92731 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
ALDH1A1 P00352 4/20 0.45
GSK3B P49841 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25498873 0.85 TSHR (0.41) TDP1HPGDMAPTMEN1KMT2A
SCHEMBL22574612 0.84 TDP1 (0.60) TDP1HPGDMAPTKDM4EMEN1
SCHEMBL28013353 0.81 TDP1 (0.50) TDP1MAPK1HPGDMAPTKDM4E
SCHEMBL501135 0.79
SCHEMBL6490422 0.78 POLB (0.55) TDP1MAPK1HPGDMAPTMEN1
SCHEMBL10484371 0.78 ALDH1A1 (0.48) TDP1HPGDMAPTKDM4EMEN1
Ammonia Solution, Strong SCHEMBL28112564 0.78 ALDH1A1 (0.48) TDP1HPGDMAPTMEN1KMT2A
Methane SCHEMBL11616604 0.78 ALDH1A1 (0.48) TDP1HPGDMAPTKDM4EMEN1
Hydrochloric Acid SCHEMBL9402312 0.78 ALDH1A1 (0.48) TDP1HPGDMAPTKDM4EMEN1
SCHEMBL9787017 0.78 ALDH1A1 (0.61) TDP1MAPK1HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138346-B 2-ethyl-4,6-disubstituted pyridine compound and preparation method thereof 上海大学 2022-11-08 CN claimed
CN-112028852-B 3-acyl isoxazole compound and preparation method thereof 常州工程职业技术学院 2022-07-26 CN claimed
CN-111289657-A Method for detecting fruit flavor components in main stream smoke of cigarette 中国烟草总公司郑州烟草研究院 2020-06-16 CN claimed
CN-111138346-A 2-ethyl-4, 6-disubstituted pyridine compound and preparation method thereof 上海大学 2020-05-12 CN claimed
EP-0550460-B1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA INC (US) 1997-04-23 EP claimed
EP-0550460-A4 1994-01-19 EP claimed
EP-0550460-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT. MOTOROLA INC (US) 1993-07-14 EP claimed
WO-1992003252-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA, INC. (US) 1992-03-05 WO claimed
US-5045128-A Printed circuits MOTOROLA, INC. (US) 1991-09-03 US claimed
CN-114901774-B Two-part curable polyurethane adhesive, cured product of two-part curable polyurethane adhesive, and polyurethane adhesive sheet 三洋化成工业株式会社 2023-11-03 CN disclosed
CN-111289657-B Method for detecting fruit flavor components in main stream smoke of cigarette 中国烟草总公司郑州烟草研究院 2022-12-20 CN disclosed
CN-111138346-B 2-ethyl-4,6-disubstituted pyridine compound and preparation method thereof 上海大学 2022-11-08 CN disclosed
CN-112028852-B 3-acyl isoxazole compound and preparation method thereof 常州工程职业技术学院 2022-07-26 CN disclosed
CN-108276555-B Polymerizable composition for plastic lens and method for producing plastic lens using same SKC株式会社 2021-11-05 CN disclosed
WO-2004016609-A1 SUBSTITUTED PYRROLOPYRIDINES ASTRAZENECA AB (SE) 2004-02-26 WO disclosed
EP-0550460-B1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA INC (US) 1997-04-23 EP disclosed
EP-0550460-A4 1994-01-19 EP disclosed
EP-0550460-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT. MOTOROLA INC (US) 1993-07-14 EP disclosed
WO-1992003252-A1 SOLDER FLUXES BEARING OXIDE REMOVERS GENERATED BY LIGHT MOTOROLA, INC. (US) 1992-03-05 WO disclosed
US-5045128-A Printed circuits MOTOROLA, INC. (US) 1991-09-03 US disclosed