SCHEMBL6490422

SCHEMBL6490422

O=C(Cc1ccco1)c1ccco1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 10/20 0.55
ALDH1A1 P00352 8/20 0.55
HPGD P15428 5/20 0.55
HSD17B10 Q99714 5/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
RECQL P46063 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
ALOX15 P16050 3/20 0.55
MAPT P10636 2/20 0.55
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
PTPN1 P18031 1/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
THRB P10828 1/20 0.47
APEX1 P27695 1/20 0.47
TSHR P16473 2/20 0.46
ESR2 Q92731 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1255897 0.82 ERCC5 (0.61) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL29999843 0.81 CES2 (0.55) POLBALDH1A1HPGDHSD17B10L3MBTL1
Furfuryl Alcohol SCHEMBL26679576 0.79 POLB (0.50) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL7087548 0.79 ALDH1A1 (0.52) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL1651850 0.79 CES2 (0.70) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL6320074 0.79 ERCC5 (0.74) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL1449481 0.78 TDP1 (0.48) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL1256721 0.77 ALDH1A1 (0.51) POLBALDH1A1HSD17B10RECQLMAPT
SCHEMBL17477706 0.77 FNTA (0.53) POLBALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL6198513 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834562-A Poria cocos acidic polysaccharide chiral stationary phase and application thereof 云南中医药大学 2024-10-25 CN claimed
CN-111018701-A Method for preparing decanediol dicarboxylate and derivatives thereof 中国科学技术大学 2020-04-17 CN claimed
US-4107283-A ION EXCHANGE CORES WITH POLYMERIC COATING, MEDICAL DIAGNOSIS NEW ENGLAND NUCLEAR CORPORATION (US) 1978-08-15 US claimed
US-12638399-B2 Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these ARCHER-DANIELS-MIDLAND COMPANY (US) 2026-05-26 US disclosed
EP-4162266-B1 METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE ARCHER DANIELS MIDLAND CO (US) 2025-06-25 EP disclosed
US-20240367156-A1 IRON-COBALT-BASED MAGNETICALLY RECOVERABLE CATALYSTS AND METHOD OF PREPARATION THEREOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-07 US disclosed
CN-220638017-U Corncob pulp removing device 北京奥科瑞丰新能源股份有限公司 2024-03-22 CN disclosed
US-20240060902-A1 METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE ARCHER DANIELS MIDLAND CO (US) 2024-02-22 US disclosed
CN-116940828-A Method for determining total aldehydes in one or more of crude 2, 5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA), and esters thereof 阿彻丹尼尔斯米德兰德公司 2023-10-24 CN disclosed
EP-4162266-A1 METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE Archer Daniels Midland Company (US) 2023-04-12 EP disclosed
CN-115356409-A Analysis method for influence of reheat time on quality of Fotiaoqiang 福建佰翔天厨食品有限公司 2022-11-18 CN disclosed
CN-110582498-A Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2019-12-17 CN disclosed
CN-103087764-A Method for producing high-grade oil-based drilling fluid base oil and mahogany petroleum sulfonate at same time BAI GUANG 2013-05-08 CN disclosed
US-20050261331-A1 Substituted pyrrolopyridines ASTRAZENECA AB (SE) 2005-11-24 US disclosed
EP-1390337-A1 PRECURSORS FOR KETONES AND ALDEHYDES Givaudan SA (CH) 2004-02-25 EP disclosed
WO-2002096850-A1 PRECURSORS FOR KETONES AND ALDEHYDES GIVAUDAN SA (CH) 2002-12-05 WO disclosed
US-4505888-A POLYMER COATED ION EXCHANGE CORES MODIFIED WITH OXIRANE COMPOUNDS E. I. DU PONT DE NEMOURS & COMPANY (US) 1985-03-19 US disclosed
US-4107283-A ION EXCHANGE CORES WITH POLYMERIC COATING, MEDICAL DIAGNOSIS NEW ENGLAND NUCLEAR CORPORATION (US) 1978-08-15 US disclosed
US-4055601-A TO AN OLEFIN ALDEHYDE, CATALYST, FURFURAL HYDROGEN ACCEPTOR SCM CORPORATION (US) 1977-10-25 US disclosed
US-3956112-A Membrane solvent extraction ALLIED CHEMICAL CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261331-A1 Substituted pyrrolopyridines ITK, WEE1, PDPK1 POLB 1097/4885ALDH1A1 1591/4885HPGD 1843/4885
US-12638399-B2 Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these FTO, AOC1, AOC2 POLB 1499/4885ALDH1A1 49/4885HPGD 384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.