Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492841 | 0.85 | ELANE (0.47) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE | |
| SCHEMBL9776402 | 0.85 | ELANE (0.47) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE | |
| SCHEMBL8409184 | 0.83 | ELANE (0.46) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE | |
| SCHEMBL9307469 | 0.82 | ELANE (0.42) | ELANEMAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL23862755 | 0.81 | CSNK2A2 (0.55) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DHFR | |
| SCHEMBL5599467 | 0.81 | CSNK2A2 (0.49) | CSNK2A2CSNK2BCSNK2A1CSNK2A3DHFR | |
| SCHEMBL5849852 | 0.80 | ELANE (0.39) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ELANE | |
| SCHEMBL11875210 | 0.79 | L3MBTL1 (0.45) | MAPTL3MBTL1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL29590360 | 0.79 | ELANE (0.52) | ELANEDHFRMAPTMAPK1L3MBTL1 | |
| SCHEMBL11729295 | 0.79 | ELANE (0.52) | ELANEDHFRMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071456-A1 | FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | disclosed |