Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496002 | 0.85 | CSNK2A2 (0.50) | ELANEDHFRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL8254791 | 0.83 | DPP4 (0.48) | ELANEDHFRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5599467 | 0.81 | CSNK2A2 (0.49) | DHFRCSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL2176548 | 0.81 | S1PR4 (0.41) | ELANEKDM4ES1PR4L3MBTL1KMT2A | |
| SCHEMBL14492841 | 0.81 | ELANE (0.47) | ELANEDHFRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5953111 | 0.80 | ELANE (0.39) | ELANES1PR4KMT2AMEN1MAPT | |
| SCHEMBL15455794 | 0.80 | ELANE (0.39) | ELANES1PR4KMT2AMEN1MAPT | |
| SCHEMBL11875210 | 0.79 | L3MBTL1 (0.45) | KDM4EL3MBTL1KMT2AMAPTALDH1A1 | |
| SCHEMBL8409184 | 0.79 | ELANE (0.46) | ELANEDHFRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL277747 | 0.79 | ELANE (0.52) | ELANEDHFRS1PR4L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5069991-A | NAPHTHOLACTAM OR ISINDOLENINE DYE | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4906541-A | Electrophotographic recording element containing a naphtholactam dye sensitizer | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |