Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.70 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14320389 | 0.87 | QDPR (0.67) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14393509 | 0.87 | QDPR (0.67) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11543936 | 0.86 | QDPR (0.66) | QDPRALDH1A1SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL14340513 | 0.84 | QDPR (0.67) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14626164 | 0.84 | QDPR (0.63) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15095880 | 0.84 | QDPR (0.59) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7687130 | 0.83 | NAMPT (0.53) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27676365 | 0.83 | QDPR (0.62) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7739767 | 0.83 | QDPR (1.00) | QDPRNAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15359063 | 0.82 | QDPR (0.54) | QDPRNAMPTKCNH2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |