Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.53 |
| ▸ | QDPR | P09417 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496802 | 0.83 | QDPR (0.70) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8912847 | 0.82 | NAMPT (0.63) | NAMPTKIT | |
| SCHEMBL23601366 | 0.80 | RIPK1 (0.45) | NAMPTQDPRALDH1A1NPC1RAB9A | |
| SCHEMBL16922689 | 0.79 | MEN1 (0.55) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL24721258 | 0.78 | MMP2 (0.52) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16978139 | 0.76 | HDAC6 (0.44) | NAMPTQDPRNPC1RAB9AMEN1 | |
| SCHEMBL15184569 | 0.75 | ALDH1A1 (0.50) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7804408 | 0.73 | PPARA (0.53) | NAMPTALDH1A1SMN1; SMN2ALOX15MEN1 | |
| SCHEMBL31488994 | 0.73 | NAMPT (0.54) | NAMPTQDPRALDH1A1MEN1KMT2A | |
| SCHEMBL17034783 | 0.72 | RIPK1 (0.42) | NAMPTQDPRNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6392051-B2 | OXIDIZING A 4-PHENYL-N-ACYLDIHYDROPYRIDINE | CLARIANT GMBH (DE) | 2002-05-21 | — | — | US | disclosed |
| US-20010021778-A1 | Process for preparing 4-(4'-carboxyphenyl)pyridine | CLARIANT GMBH | 2001-09-13 | — | — | US | disclosed |
| EP-1125926-A1 | Process for the preparation of 4-(4'-carboxyphenyl)pyridine | Clariant GmbH (DE) | 2001-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021778-A1 | Process for preparing 4-(4'-carboxyphenyl)pyridine | NOX4, CBR1, CBR3 | NAMPT 2197/4885QDPR 86/4885ALDH1A1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.