Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496962 | 0.89 | TRPA1 (0.51) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL14496988 | 0.89 | TRPA1 (0.51) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL5543004 | 0.85 | TRPA1 (0.47) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL14497054 | 0.85 | TRPA1 (0.47) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL14496995 | 0.85 | TRPA1 (0.47) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL5548531 | 0.85 | L3MBTL1 (0.48) | L3MBTL1MAPK1PTK2TDP1NPC1 | |
| SCHEMBL14496990 | 0.84 | SYK (0.51) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL14497000 | 0.84 | TRPA1 (0.45) | TRPA1L3MBTL1MAPK1PTK2TDP1 | |
| SCHEMBL14496966 | 0.83 | HTT (0.48) | TRPA1L3MBTL1MAPK1PTK2NPC1 | |
| SCHEMBL14497038 | 0.83 | TRPA1 (0.44) | TRPA1L3MBTL1MAPK1PTK2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129371-A1 | Novel ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
| US-20070129371-A1 | Novel ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129371-A1 | Novel ethylenediamine derivatives | C1R, C9, C1S | TRPA1 1764/4885CA1 1918/4885CA2 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.