Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.80 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.80 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.80 |
| ▸ | VDR | P11473 | 2/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.74 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485302 | 0.96 | GPBAR1 (0.85) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL25658157 | 0.92 | GPBAR1 (0.81) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL18199508 | 0.92 | GPBAR1 (0.81) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL14485375 | 0.91 | GPBAR1 (0.78) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL1977807 | 0.91 | GPBAR1 (0.80) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL19577615 | 0.91 | GPBAR1 (0.80) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL12250467 | 0.91 | GPBAR1 (0.80) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL19549236 | 0.90 | GPBAR1 (0.79) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL19577237 | 0.90 | GPBAR1 (0.79) | GPBAR1ABCC4SLC10A2VDRTBXA2R | |
| SCHEMBL19549232 | 0.90 | GPBAR1 (0.79) | GPBAR1ABCC4SLC10A2VDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235678-B2 | Bile acid derived steroidal dimers with novel amphiphilic topology having antifungal activity | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-26 | — | — | US | disclosed |