Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.81 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.81 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.81 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | CA1 | P00915 | 6/20 | 0.70 |
| ▸ | CA2 | P00918 | 6/20 | 0.70 |
| ▸ | VDR | P11473 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25658157 | 1.00 | GPBAR1 (0.81) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485302 | 0.95 | GPBAR1 (0.85) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549288 | 0.93 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19549290 | 0.93 | GPBAR1 (0.79) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14485375 | 0.92 | GPBAR1 (0.78) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL1977807 | 0.92 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL12250467 | 0.92 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL19577615 | 0.92 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL14497558 | 0.92 | GPBAR1 (0.80) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A | |
| SCHEMBL25269524 | 0.91 | GPBAR1 (0.77) | GPBAR1SLC10A2ABCC4TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2024-06-27 | — | — | US | disclosed |
| US-20230331766-A1 | METHOD FOR MASS-PRODUCING SODIUM TAURODEOXYCHOLATE | SHAPERON INC. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180207276-A1 | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2018-07-26 | — | — | US | disclosed |
| US-10010589-B2 | — | — | 2018-07-03 | — | — | US | disclosed |
| US-20160317623-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331766-A1 | METHOD FOR MASS-PRODUCING SODIUM TAURODEOXYCHOLATE | HSD11B1, HSD11B2, DHCR7 | GPBAR1 382/4885SLC10A2 43/4885ABCC4 4177/4885 |
| US-20160317623-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | SGMS1, SGMS2, PHOSPHO1 | GPBAR1 893/4885SLC10A2 100/4885ABCC4 1985/4885 |
| US-10010589-B2 | — | TYMP, MTAP, TUBB6 | GPBAR1 2193/4885SLC10A2 268/4885ABCC4 1520/4885 |
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | SGMS1, SGMS2, PHOSPHO1 | GPBAR1 893/4885SLC10A2 100/4885ABCC4 1985/4885 |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | SGMS1, SGMS2, PHOSPHO1 | GPBAR1 893/4885SLC10A2 100/4885ABCC4 1985/4885 |
| US-20180207276-A1 | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF | HDGF, ELANE, CD47 | GPBAR1 2816/4885SLC10A2 1205/4885ABCC4 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.