Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | TTK | P33981 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17739710 | 0.85 | GPR84 (0.41) | ALOX15ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL28364743 | 0.83 | MEN1 (0.40) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL28310780 | 0.82 | GPR84 (0.46) | ALDH1A1MAPTGPR84NPSR1MEN1 | |
| SCHEMBL15912446 | 0.81 | TNIK (0.32) | — | |
| SCHEMBL27483035 | 0.81 | ALOX15 (0.39) | ALOX15ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL28147077 | 0.81 | DPP4 (0.40) | ALOX15ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL18642527 | 0.79 | NR1H2 (0.42) | ALOX15ALDH1A1KDM4EHPGDTTK | |
| SCHEMBL27872988 | 0.77 | KDM4E (0.45) | PTGS1ALOX15ALDH1A1MAPTKDM4E | |
| SCHEMBL9706893 | 0.77 | HPGD (0.36) | ALOX15ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2387037 | 0.74 | AKT2 (0.44) | PTGS1PTGS2ALOX15ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038589-A1 | Methods and compositions for targeting Tregs using CCR8 inhibitors | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2023-02-09 | — | — | US | disclosed |
| CN-106146417-B | A method of 4- aryl-NH-1,2,3- triazole is prepared using aldehyde sodium bisulfite adduct | 海南师范大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-106146417-A | A kind of method utilizing aldehyde sodium bisulfite adduct to prepare 4-aryl-NH-1,2,3-triazole | 海南师范大学 | 2016-11-23 | — | — | CN | disclosed |
| US-9340578-B2 | Inhibitors targeting human ghrelin O-acyltransferase | SYRACUSE UNIVERSITY (US) | 2016-05-17 | — | — | US | disclosed |
| CN-103554760-A | Anti-ageing PVC (Polyvinyl Chloride) surface tube | ANHUI GUOTONE HIGH TECH PIPES INDUSTRY CO LTD | 2014-02-05 | — | — | CN | disclosed |
| US-7235548-B2 | Compounds and their use as positive AMPA receptor modulators | NEUROSEARCH A/S (DK) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230038589-A1 | Methods and compositions for targeting Tregs using CCR8 inhibitors | CCR8, CCR1, CCR3 | PTGS1 578/4885PTGS2 954/4885ALOX15 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.