Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 10/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 11/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498687 | 0.97 | PRKCA (0.54) | PRKCADYRK1APAX8PRKD3PRKCG | |
| Becatecarin SCHEMBL5953888 | 0.86 | PRKCA (0.78) | PRKCADYRK1APAX8PRKD3PRKCG | |
| Becatecarin SCHEMBL31237559 | 0.86 | PRKCA (0.78) | PRKCADYRK1APAX8PRKD3PRKCG | |
| Becatecarin SCHEMBL29378739 | 0.86 | PRKCA (0.78) | PRKCADYRK1APAX8PRKD3PRKCG | |
| Becatecarin SCHEMBL5953787 | 0.86 | PRKCA (0.78) | PRKCADYRK1APAX8PRKD3PRKCG | |
| Becatecarin SCHEMBL6385483 | 0.84 | PRKCA (0.74) | PRKCADYRK1APAX8PRKD3PRKCG | |
| SCHEMBL6385491 | 0.80 | PRKCA (0.67) | PRKCADYRK1APAX8PRKD3PRKCG | |
| SCHEMBL26846490 | 0.78 | PRKCA (0.65) | PRKCADYRK1APAX8PRKD3PRKCG | |
| SCHEMBL6736119 | 0.78 | PRKCA (0.77) | PRKCADYRK1APAX8PRKCQTOP1 | |
| SCHEMBL6735510 | 0.78 | PRKCA (0.59) | PRKCADYRK1APAX8PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227019-B2 | Process for the preparation of rebeccamycin and analogs thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| US-7227019-B2 | Process for the preparation of rebeccamycin and analogs thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-05 | — | — | US | disclosed |