SCHEMBL144989

SCHEMBL144989

O=C(O)c1ccccc1SSc1ccccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 1.00
CA12 O43570 2/20 0.63
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
CA4 P22748 2/20 0.63
CA7 P43166 2/20 0.63
CA9 Q16790 2/20 0.63
ALDH1A1 P00352 5/20 0.62
ALOX15 P16050 1/20 0.62
CYP1A2 P05177 1/20 0.61
RAB9A P51151 3/20 0.55
KDM4E B2RXH2 2/20 0.52
HMGB1 P09429 1/20 0.52
HPGD P15428 1/20 0.52
CA6 P23280 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380162 1.00 POLB (1.00) POLBCA12CA1CA2CA4
SCHEMBL28550182 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9132867 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9132242 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9136394 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9133015 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9134919 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9134295 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL28576293 0.98 POLB (0.95) POLBCA12CA1CA2CA4
SCHEMBL9136280 0.98 POLB (0.95) POLBCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080731-A Weather-resistant high-hardness composite anticorrosive paint and preparation method thereof 2026-05-26 CN claimed
CN-117186885-B Preparation method of aggregation-induced emission carbon dots with adjustable emission wavelength 山东理工大学 2025-05-23 CN claimed
US-20250163101-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE Research & Business Foundation Sungkyunkwan University (KR) 2025-05-22 US claimed
WO-2025074986-A1 MODIFIED POLYCARBONATE, METHOD FOR PRODUCING MODIFIED POLYCARBONATE, AND RESIN COMPOSITION 株式会社カネカ 2025-04-10 WO claimed
CN-119733387-A Dichloromethane-resistant VOCs recovery organic film and preparation method thereof 江苏久膜高科技股份有限公司 2025-04-01 CN claimed
WO-2025049222-A1 ELECTROLYTE COMPRISING CYCLIC QUATERNARY AMMONIUM IONIC LIQUID AND SOLVENT WITH HIGH BOILING POINT AND BATTERIES COMPRISING SAME FACTORIAL INC. (US) 2025-03-06 WO claimed
WO-2025049220-A1 ELECTROLYTE COMPRISING IMIDAZOLIUM IONIC LIQUID AND SOLVENT WITH HIGH BOILING POINT AND BATTERIES COMPRISING SAME FACTORIAL INC. (US) 2025-03-06 WO claimed
CN-119524583-A System and method for recycling dichloromethane from waste gas 江苏久膜高科技股份有限公司 2025-02-28 CN claimed
CN-119285983-A Reduction-response metal organic framework material and preparation method and application thereof 武汉理工大学 2025-01-10 CN claimed
EP-4488290-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE ABTIS Co., Ltd. (KR) 2025-01-08 EP claimed
EP-0520574-A1 Thioxanthone derivatives GREAT LAKES FINE CHEMICALS LIMITED (GB) 1992-12-30 EP claimed
EP-0464388-A1 Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) 1992-01-08 EP claimed
US-4493802-A Preparation of o,o'-dithiodibenzoic acids BASF AKTIENGESELLSCHAFT (DE) 1985-01-15 US claimed
EP-0085181-B1 PROCESS FOR PREPARING O,O'-DITHIODIBENZOIC ACIDS BASF Aktiengesellschaft (DE) 1984-10-03 EP claimed
US-4307031-A DIAZOTIZATION THEN COPPER CATALYZED REACTION WITH CARBON DISULFIDE THE SHERWIN-WILLIAMS COMPANY (US) 1981-12-22 US claimed
US-4122111-A FUNGICIDES ISF SPA (IT) 1978-10-24 US claimed
US-4043942-A Modified nickel catalyst systems and their use in reductive alkylation reactions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-23 US claimed
US-4036709-A ORGANIC DISULFIDE M & T CHEMICALS INC. (US) 1977-07-19 US claimed
US-3984292-A ACTIVATOR SCHERING AKTIENGESELLSCHAFT (DT) 1976-10-05 US claimed
US-3947292-A Preparation of an alkaline iron electrode material using sulfur acids WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163101-A1 METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE TST, DHFR, FCGRT POLB 3202/4885CA12 661/4885CA1 955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.