SCHEMBL14500910

SCHEMBL14500910

Cc1nc(N)c2ncn(CCOCCCc3nccs3)c2c1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.31
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4794638 0.99 FGFR1 (0.30) FGFR1CDK1CCNB1CCNE1CDK2
SCHEMBL4876384 0.82 KMT2A (0.31)
SCHEMBL2059062 0.81 TLR7 (0.48)
SCHEMBL4792810 0.81 TLR7 (0.41)
SCHEMBL4792716 0.80 TLR8 (0.46)
SCHEMBL4791915 0.73 LMNA (0.34) FGFR1CDK1CCNB1CCNE1CDK2
SCHEMBL6094919 0.70 ALDH1A1 (0.39) CDK1CCNB1CCNE1CDK2
SCHEMBL4770564 0.70 LMNA (0.47)
SCHEMBL4791879 0.69 TLR7 (0.35)
SCHEMBL4794870 0.69 ADORA2A (0.35) CDK1CCNB1CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220758-B2 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-22 US disclosed
US-7220758-B2 Ether substituted imidazopyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-22 US disclosed