Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | ACR | P10323 | 3/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501370 | 0.95 | PRSS1 (0.48) | ESR1ESR2PRSS1ACRHAO1 | |
| SCHEMBL14501372 | 0.92 | KMT2A (0.51) | ESR1ESR2PRSS1ACRHAO1 | |
| SCHEMBL28692695 | 0.81 | MEN1 (0.61) | PRSS1ACRHAO1CYP3A4KMT2A | |
| SCHEMBL4672150 | 0.79 | ALDH1A1 (0.51) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14501375 | 0.78 | KMT2A (0.53) | ESR1ESR2PRSS1ACRMAPT | |
| SCHEMBL4354653 | 0.78 | MAPT (0.52) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL10411916 | 0.76 | MAPT (0.51) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL14501378 | 0.76 | FABP7 (0.51) | ESR1ESR2PRSS1ACRHAO1 | |
| SCHEMBL13023078 | 0.76 | HAO1 (0.49) | ESR1ESR2PRSS1ACRHAO1 | |
| SCHEMBL13292713 | 0.75 | ESR1 (0.53) | ESR1ESR2PRSS1ACRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211642-B2 | Thermosetting aromatic dielectric material | THE BOARD OF TRUSTEES OF THE UNIVERISTY OF ILLINOIS (US) | 2007-05-01 | — | — | US | disclosed |