Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662184 | 0.98 | CYP3A4 (0.39) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| SCHEMBL11681580 | 0.95 | CYP3A4 (0.38) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| SCHEMBL18214942 | 0.95 | CYP3A4 (0.38) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| SCHEMBL16859262 | 0.95 | CYP3A4 (0.38) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| SCHEMBL16192583 | 0.89 | CYP3A4 (0.33) | TDP1CYP3A4TAAR1SLC6A2 | |
| Carbon Monoxide SCHEMBL11677542 | 0.89 | CYP3A4 (0.33) | TDP1CYP3A4TAAR1SLC6A2CYP2C19 | |
| SCHEMBL4988388 | 0.89 | ESR1 (0.33) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| Formaldehyde SCHEMBL17495187 | 0.89 | CYP3A4 (0.33) | TDP1CYP3A4TAAR1SLC6A2CYP2C19 | |
| SCHEMBL15484320 | 0.86 | CYP3A4 (0.35) | TDP1CYP3A4TAAR1SLC6A2ESR1 | |
| SCHEMBL8000342 | 0.86 | CYP3A4 (0.35) | TDP1CYP3A4TAAR1SLC6A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910272-B2 | Dye-containing photosensitive composition, color filter using the same, and production method thereof | FUJIFILM CORPORATION (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20070190435-A1 | Dye-containing photosensitive composition, color filter using the same, and production method thereof | FUJIFILM CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070184366-A1 | DYE CONTAINING CURABLE COMPOSITION, COLOR FILTER, AND PROCESS OF PREPARING COLOR FILTER | FUJIFILM CORPORATION | 2007-08-09 | — | — | US | disclosed |
| US-20070099096-A1 | Dye-containing curable composition, color filter and method of producing thereof | FUJIFILM CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20040185372-A1 | Dye-containing curable composition, color filter, and process of preparing color filter | FUJI PHOTO FILM CO., LTD. | 2004-09-23 | — | — | US | disclosed |