SCHEMBL16192583

SCHEMBL16192583

CC(CP(c1ccccc1)c1ccccc1)(CP(c1ccccc1)c1ccccc1)CP(c1ccccc1)c1ccccc1.Cl[Rh](Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TAAR1 Q96RJ0 2/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662184 0.91 CYP3A4 (0.39) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL11681580 0.89 CYP3A4 (0.38) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL16859262 0.89 CYP3A4 (0.38) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL18214942 0.89 CYP3A4 (0.38) CYP3A4TDP1TAAR1SLC6A2
Hydrochloric Acid SCHEMBL1450177 0.89 TDP1 (0.38) CYP3A4TDP1TAAR1SLC6A2
Carbon Monoxide SCHEMBL11677542 0.83 CYP3A4 (0.33) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL4988388 0.83 ESR1 (0.33) CYP3A4TDP1TAAR1SLC6A2
Formaldehyde SCHEMBL17495187 0.83 CYP3A4 (0.33) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL8966352 0.82 CYP3A4 (0.39) CYP3A4TDP1TAAR1SLC6A2
SCHEMBL15484320 0.81 CYP3A4 (0.35) CYP3A4TDP1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344506-A1 NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-12-03 US claimed
US-9073956-B1 Dihydro-1H-phosphole 1-oxide derivatives and preparation method thereof KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-07-07 US claimed
EP-2796511-B1 POLYMER ELECTROLYTE COMPOSITION, AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY AND SOLID POLYMER FUEL CELL EACH USING SAME TORAY INDUSTRIES (JP) 2020-03-04 EP disclosed
US-9685674-B2 Polymer electrolyte composition, and polymer electrolyte membrane, membrane electrode assembly and solid polymer fuel cell each using same TORAY INDUSTRIES, INC. (JP) 2017-06-20 US disclosed
US-9493494-B2 Phosphinine oxide derivative and preparation method thereof KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2016-11-15 US disclosed
US-20150344506-A1 NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-12-03 US disclosed
US-9073956-B1 Dihydro-1H-phosphole 1-oxide derivatives and preparation method thereof KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-07-07 US disclosed
US-20140377686-A1 POLYMER ELECTROLYTE COMPOSITION, AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY AND SOLID POLYMER FUEL CELL EACH USING SAME TORAY INDUSTRIES, INC. (JP) 2014-12-25 US disclosed
EP-2796511-A1 POLYMER ELECTROLYTE COMPOSITION, AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY AND SOLID POLYMER FUEL CELL EACH USING SAME Toray Industries, Inc. (JP) 2014-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344506-A1 NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF PHOSPHO1, PPIP5K2, ITPA CYP3A4 982/4885TDP1 4007/4885TAAR1 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.