Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.56 |
| ▸ | PPARG | P37231 | 11/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369740 | 1.00 | PPARA (0.56) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5353508 | 1.00 | PPARA (0.56) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5353516 | 1.00 | PPARA (0.56) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5353512 | 1.00 | PPARA (0.56) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL14501972 | 0.91 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6152285 | 0.90 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5364055 | 0.90 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5364058 | 0.90 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5364847 | 0.85 | LMNA (0.66) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5364849 | 0.85 | LMNA (0.66) | PPARAPPARGLMNAL3MBTL1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |