Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.52 |
| ▸ | PPARG | P37231 | 14/20 | 0.49 |
| ▸ | PPARD | Q03181 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501883 | 0.91 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5369740 | 0.91 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5353508 | 0.91 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5353516 | 0.91 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5353512 | 0.91 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL5364055 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL6152285 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5364058 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL14532664 | 0.82 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL14501971 | 0.80 | PPARA (0.50) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220880-B2 | Amide linker peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-05-22 | — | — | US | disclosed |