Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | ACACA | Q13085 | 6/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295035 | 0.90 | ACACB (0.45) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL13266752 | 0.88 | ACACB (0.42) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL11932139 | 0.88 | ACACB (0.52) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL12778736 | 0.88 | ACACB (0.52) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL13105390 | 0.87 | ACACB (0.41) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL14490552 | 0.82 | ACACB (0.36) | ACACBACACA | |
| SCHEMBL12778724 | 0.81 | ACACB (0.40) | ACACBACACABACE1CHRM2CHRM4 | |
| SCHEMBL2850592 | 0.80 | ACACB (0.52) | ACACBACACACHRM2CHRM4CHRM5 | |
| SCHEMBL14400275 | 0.79 | ACACB (0.42) | ACACBACACABACE1 | |
| SCHEMBL2850600 | 0.79 | ACACB (0.54) | ACACBACACACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | ACACB 936/4885ACACA 947/4885BACE1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.