TRIP13 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24350851	0.62	6/20
SCHEMBL24352104	0.62	6/20
SCHEMBL31111525	1.00	2/20
SCHEMBL13936105	0.50	2/20
SCHEMBL13955065	0.49	2/20
SCHEMBL14069644	0.45	2/20
SCHEMBL26671388	0.45	2/20
SCHEMBL17527988	0.44	2/20
SCHEMBL17528015	0.44	2/20
SCHEMBL20207079	0.44	2/20
SCHEMBL20207080	0.44	2/20
SCHEMBL20207155	0.44	2/20
SCHEMBL25475593	0.44	2/20
SCHEMBL17683641	0.43	2/20
SCHEMBL20280168	0.43	2/20
SCHEMBL21577183	0.42	2/20
SCHEMBL9492443	0.42	2/20
SCHEMBL17683645	0.39	2/20
SCHEMBL4026751	0.38	2/20
SCHEMBL13661744	0.38	2/20

Clinical trials — most relevant to TRIP13 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia	PHASE3	COMPLETED
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men	PHASE3	ACTIVE_NOT_RECRUITING
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors	PHASE1	COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel	PHASE1	COMPLETED
Management of Abnormally Fertilized Zygotes? InVitro Correction of 3PN	EARLY_PHASE1	COMPLETED
Prospective Genetic Study in Patients With Ovarian Insufficiency	nan	UNKNOWN
PCM1-JAK2 in Therapy Related Neoplasms	nan	UNKNOWN
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort	nan	UNKNOWN
Telomere Repair Gene Mutation in Inflammatory Bowel Disease	nan	COMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Study of the Effect of Innate on the Inflammatory Response to Endotoxin	nan	RECRUITING
Genomic Study of Congenital Malformation	nan	UNKNOWN
Enhanced Linkage Maps From Family-Based Genetics Studies	nan	COMPLETED
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility	nan	COMPLETED
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility	nan	RECRUITING
Telomeres Length in Israeli Fibrotic ILD Patients	nan	ENROLLING_BY_INVITATION
Development of a Newborn Screening Assay for Angelman Syndrome and Prader-Willi Syndrome	nan	COMPLETED
Genetic Studies Spermatogenic Failure	nan	COMPLETED
Family Blood Pressure Program - SAPPHIRe Network	nan	COMPLETED
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy	nan	COMPLETED
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities	nan	COMPLETED
Importance of the Microtubule Cytoskeleton in Oocyte Competence	nan	COMPLETED
The Role of NLRP Gene Family (NLRP1~14) in Recurrent Miscarriage and Infertility	nan	COMPLETED
Predictive Value of Embryonic Testing	nan	COMPLETED
Positional Cloning of the Gene(s) Responsible for Alagille Syndrome	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Zona Pellucida Bound Sperm vs. Embryologist Selected Sperm for Intracytoplasmic Sperm Injection	nan	COMPLETED
AI-Based Fine Morphological Subtyping of Myeloma Single Cells for Predicting FISH Abnormalities	nan	ENROLLING_BY_INVITATION
Study of Abnormally Fertilized Embryos	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a TRIP13 binder may also engage these)

Protein	Name	Similarity
E2R222	—	1.000	E2R222 →
Q5XHZ9	—	1.000	Q5XHZ9 →
D3K5L7	—	1.000	D3K5L7 →
Q3UA06	—	0.994	Q3UA06 →
E1C6Q1	—	0.984	E1C6Q1 →
CDC16	Cell division cycle protein 16 homolog	0.949	landscape →
DHX9	ATP-dependent RNA helicase A	0.946	landscape →
Q9JIB4	—	0.946	Q9JIB4 →
A7MB76	—	0.945	A7MB76 →
Q5R874	—	0.945	Q5R874 →
Q8R349	—	0.943	Q8R349 →
Q5M887	—	0.943	Q5M887 →
Q6PBY7	—	0.942	Q6PBY7 →
RFC3	Replication factor C subunit 3	0.942	landscape →
A5PLN9	—	0.942	A5PLN9 →
Q6NRT5	—	0.941	Q6NRT5 →
Q5RCG0	—	0.941	Q5RCG0 →
Q99LD4	—	0.941	Q99LD4 →
Q2TBV1	—	0.940	Q2TBV1 →
P97834	—	0.940	P97834 →
Q5RBV0	—	0.940	Q5RBV0 →
A0JN27	—	0.940	A0JN27 →
Q96LI5	—	0.940	Q96LI5 →
Q3TIR1	—	0.940	Q3TIR1 →
GPS1	COP9 signalosome complex subunit 1	0.939	landscape →
Q28141	—	0.939	Q28141 →
Q0V7M0	—	0.938	Q0V7M0 →
Q6GPR5	—	0.938	Q6GPR5 →
P17427	—	0.938	P17427 →
Q96DM3	—	0.938	Q96DM3 →