Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 3/20 | 0.73 |
| ▸ | GALR1 | P47211 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | IDH2 | P48735 | 3/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | CTSB | P07858 | 1/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503046 | 0.85 | GALR2 (0.55) | GALR2GALR1MAPTIDH2CTSL | |
| SCHEMBL10143793 | 0.85 | GALR2 (1.00) | GALR2GALR1MAPTIDH2CTSL | |
| SCHEMBL14503014 | 0.85 | GALR2 (0.61) | GALR2GALR1MAPTIDH2CTSS | |
| SCHEMBL14505011 | 0.83 | GALR2 (0.55) | GALR2GALR1MAPTIDH2CTSL | |
| SCHEMBL5395758 | 0.81 | CTSL (0.55) | GALR2GALR1MAPTIDH2CTSL | |
| SCHEMBL10143409 | 0.79 | GALR2 (0.82) | GALR2GALR1GBA1KMT2AMEN1 | |
| SCHEMBL30568799 | 0.79 | IDH2 (1.00) | MAPTIDH2LMNASMN1; SMN2HTT | |
| SCHEMBL14504821 | 0.78 | MAPT (0.56) | GALR2GALR1MAPTIDH2CTSS | |
| SCHEMBL10143426 | 0.77 | GALR2 (1.00) | GALR2GALR1 | |
| SCHEMBL14503558 | 0.77 | LMNA (0.71) | MAPTIDH2LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |