Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | IDH2 | P48735 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504241 | 0.96 | NPSR1 (0.68) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503144 | 0.83 | NPSR1 (0.94) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14504268 | 0.81 | NPSR1 (0.63) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503724 | 0.81 | NPSR1 (0.82) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503165 | 0.80 | NPSR1 (0.62) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503192 | 0.80 | NPSR1 (0.62) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503346 | 0.80 | NPSR1 (0.62) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11807869 | 0.80 | NPSR1 (0.93) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503595 | 0.79 | RAB9A (0.54) | NPSR1LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14503558 | 0.78 | LMNA (0.71) | NPSR1LMNASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |