Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381103 | 0.82 | OPRD1 (0.51) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1123942 | 0.79 | OPRD1 (0.56) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1124061 | 0.79 | OPRD1 (0.56) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1123707 | 0.77 | OPRD1 (0.46) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1123749 | 0.77 | OPRD1 (0.46) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1838291 | 0.77 | AKR1C1 (0.68) | HSD11B1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL1734335 | 0.76 | KDM4E (0.67) | OPRD1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8324812 | 0.76 | OPRM1 (0.63) | OPRD1HSD11B1CA12CA1CA2 | |
| SCHEMBL3737199 | 0.75 | AKR1C1 (0.70) | OPRD1ALDH1A1HSD11B1MEN1KMT2A | |
| SCHEMBL12928712 | 0.75 | AKR1C1 (0.64) | OPRD1ALDH1A1HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |