Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378092 | 0.93 | ACHE (0.38) | NPSR1LMNAACHEHTT | |
| SCHEMBL14533202 | 0.87 | NPSR1 (0.60) | NPSR1LMNAGAAKMT2AMAPT | |
| SCHEMBL5380907 | 0.80 | HTR7 (0.44) | NPSR1LMNAGAAKMT2AMAPT | |
| SCHEMBL5380797 | 0.78 | HTT (0.43) | NPSR1LMNAGAAMAPTALDH1A1 | |
| SCHEMBL5382285 | 0.78 | CDK1 (0.39) | LMNAMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL5384017 | 0.78 | IDH1 (0.41) | LMNAMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL5382850 | 0.78 | CDK1 (0.39) | LMNAMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL5382275 | 0.78 | CDK1 (0.39) | LMNAMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL14503245 | 0.78 | IDH2 (0.42) | LMNAMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL5383953 | 0.77 | MKNK2 (0.40) | NPSR1LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |