Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503158 | 0.95 | ACHE (0.55) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503132 | 0.95 | ACHE (0.55) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503647 | 0.91 | ACHE (0.46) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL5383850 | 0.91 | ACHE (0.49) | ACHEALDH1A1CNR2LMNACA12 | |
| SCHEMBL14503568 | 0.90 | ACHE (0.51) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503612 | 0.90 | ACHE (0.49) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503641 | 0.90 | ACHE (0.49) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503572 | 0.89 | CNR2 (0.49) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503390 | 0.89 | LMNA (0.51) | ACHEALDH1A1CNR2CNR1LMNA | |
| SCHEMBL14503749 | 0.88 | ACHE (0.47) | ACHEALDH1A1CNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |