Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GBA1 | P04062 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503258 | 0.89 | LMNA (0.53) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503838 | 0.87 | HTT (0.50) | LMNASMN1; SMN2HTTNPSR1MEN1 | |
| SCHEMBL14503261 | 0.80 | NPSR1 (0.57) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL5384843 | 0.80 | KDM4E (0.39) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503260 | 0.78 | LMNA (0.64) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503648 | 0.78 | LMNA (0.63) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503890 | 0.77 | LMNA (0.54) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503885 | 0.77 | LMNA (0.53) | LMNASMN1; SMN2HTTNPSR1MAPT | |
| SCHEMBL14503396 | 0.76 | GBA1 (0.51) | LMNASMN1; SMN2HTTNPSR1MEN1 | |
| SCHEMBL14503873 | 0.76 | KDM4E (0.52) | LMNASMN1; SMN2NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |