Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504164 | 0.80 | HTT (0.54) | SMN1; SMN2LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL3640140 | 0.80 | KDM4E (0.58) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5383928 | 0.80 | BCDIN3D (0.41) | DPP4BCDIN3DGAA | |
| Hydrochloric Acid SCHEMBL3638140 | 0.79 | KDM4E (0.60) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14503396 | 0.76 | GBA1 (0.51) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14504152 | 0.76 | LMNA (0.53) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14503783 | 0.74 | NPSR1 (0.44) | KDM4ESMN1; SMN2LMNANPSR1POLB | |
| SCHEMBL14503838 | 0.74 | HTT (0.50) | SMN1; SMN2LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL14503258 | 0.73 | LMNA (0.53) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14503296 | 0.72 | MAPT (0.63) | KDM4ESMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |