Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14505242 | 0.91 | SMN1; SMN2 (0.51) | EGLN1NPC1RAB9AL3MBTL1PTGS2 | |
| SCHEMBL14504837 | 0.89 | EGLN1 (0.60) | EGLN1RAB9AL3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL14505193 | 0.87 | SMN1; SMN2 (0.48) | NPC1RAB9AL3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL14503855 | 0.87 | LMNA (0.49) | NPC1RAB9APTGS2SMN1; SMN2MAPT | |
| SCHEMBL5376284 | 0.86 | EGLN1 (0.46) | EGLN1KDM4EKDR | |
| SCHEMBL5376246 | 0.86 | EGLN1 (0.46) | EGLN1KDM4EKDR | |
| SCHEMBL14505036 | 0.84 | PIM1 (0.57) | NPC1RAB9AKDM4EL3MBTL1PTGS2 | |
| SCHEMBL14503828 | 0.83 | SMN1; SMN2 (0.53) | NPC1RAB9AL3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL14505122 | 0.83 | CA12 (0.48) | NPC1RAB9AL3MBTL1PTGS2SMN1; SMN2 | |
| SCHEMBL14505237 | 0.83 | PTGS2 (0.49) | NPC1RAB9APTGS2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |