Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102338 | 0.77 | TSHR (0.64) | TSHRPSMD14HSD11B1 | |
| SCHEMBL20154126 | 0.70 | — | — | |
| SCHEMBL840077 | 0.70 | PSMD14 (0.44) | TSHRPSMD14HSD11B1 | |
| SCHEMBL24743766 | 0.63 | TSHR (0.51) | TSHRPSMD14 | |
| SCHEMBL18410888 | 0.63 | TSHR (0.56) | TSHRPSMD14 | |
| SCHEMBL24443096 | 0.63 | TSHR (0.56) | TSHRPSMD14 | |
| SCHEMBL25459913 | 0.61 | KDM4E (0.36) | TSHR | |
| SCHEMBL16080202 | 0.61 | — | — | |
| SCHEMBL3080998 | 0.61 | PSMD14 (0.77) | TSHRPSMD14HSD11B1 | |
| SCHEMBL19261446 | 0.60 | TSHR (0.44) | TSHRPSMD14HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | HAFFNER CURT D | 2007-05-03 | — | — | US | disclosed |
| US-7173134-B2 | Selective RXR ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099991-A1 | SELECTIVE RXR LIGANDS | RXRB, RXRA, RXRG | TSHR 83/4885PSMD14 2658/4885HSD11B1 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.