SCHEMBL14509342

SCHEMBL14509342

C=CC(=O)OC(C)(C)COCC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 8/20 0.37
ALDH1A1 P00352 5/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26078844 0.81 THRB (0.40) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12330928 0.80 THRB (0.63) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL14509324 0.80 TSHR (0.52) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL22563728 0.80 ALDH1A1 (0.53) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL14509386 0.80 ALDH1A1 (0.39) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL302801 0.79 THRB (0.43) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL554711 0.79 THRB (0.41) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL25382779 0.78 ALDH1A1 (0.38) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12835641 0.78 ALDH1A1 (0.38) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL8731568 0.78 THRB (0.40) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223516-B2 Positive type photoresist composition FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-7223516-B2 Positive type photoresist composition FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed