Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6238486 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL1451323 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL17491843 | 0.80 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL949646 | 0.78 | CA12 (0.31) | — | |
| Hydrochloric Acid SCHEMBL17491845 | 0.76 | GAA (0.31) | — | |
| Bromide SCHEMBL28391750 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6862031 | 0.76 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL320093 | 0.76 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2121675 | 0.76 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2121676 | 0.76 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936672-B2 | Mold addition polymerization of norbornene-type monomers using group 10 metal complexes | SUMITOMO BAKELITE CO., LTD. (JP) | 2005-08-30 | — | — | US | claimed |
| EP-1155057-B1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | SUMITOMO BAKELITE CO (JP) | 2005-06-22 | — | — | EP | claimed |
| US-20030120006-A1 | In mold addition polymerization of norbornene-type monomers using group 10 metal complexes | THE B.F. GOODRICH COMPANY | 2003-06-26 | — | — | US | claimed |
| US-6350832-B1 | CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION | THE B. F. GOODRICH COMPANY | 2002-02-26 | — | — | US | claimed |
| EP-1155057-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | The B.F.Goodrich Co. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000034344-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | THE B.F.GOODRICH COMPANY (US) | 2000-06-15 | — | — | WO | claimed |
| US-9076986-B2 | Gas barrier laminate and circularly polarizing plate | ZEON CORPORATION (JP) | 2015-07-07 | — | — | US | disclosed |
| US-8609005-B2 | Stretched film of addition polymer consisting of norbornene compound, process for producing the same and use thereof | ZEON CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| EP-2028222-B1 | ORIENTED FILM OF ADDITION POLYMER OF NORBORNENE COMPOUND ALONE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | ZEON CORP (JP) | 2013-01-30 | — | — | EP | disclosed |
| US-20130021667-A1 | GAS BARRIER LAMINATE AND CIRCULARLY POLARIZING PLATE | ZEON CORPORATION (JP) | 2013-01-24 | — | — | US | disclosed |
| US-8013090-B2 | Film comprising norbornene compound addition polymer | ZEON CORPORATION (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7910674-B2 | Especially a copolymer of norbornene and/or alkylnorbornene and (trialkoxysilylalkyl)norbornene; optical articles such as ophthalmic lenses, wave guides, optical fibers, and optical adhesives | PROMERUS, LLC (US) | 2011-03-22 | — | — | US | disclosed |
| US-20090297870-A1 | Norbornene Compound Addition Polymer Film, Process for Production Thereof, and Use Thereof | ZEON CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20020052454-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | SUMITOMO BAKELITE CO., LTD. (JP) | 2002-05-02 | — | — | US | disclosed |
| US-6350832-B1 | CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION | THE B. F. GOODRICH COMPANY | 2002-02-26 | — | — | US | disclosed |
| WO-2002010810-A2 | OPTICAL WAVEGUIDES AND METHODS FOR MAKING THE SAME | GOODRICH CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| EP-1155057-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | The B.F.Goodrich Co. (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1034196-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | THE B.F. GOODRICH COMPANY (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-2000034344-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | THE B.F.GOODRICH COMPANY (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000020472-A1 | CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS | THE B.F. GOODRICH COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |