Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511819 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1NR3C1 | |
| SCHEMBL14511793 | 0.84 | KMT2A (0.40) | PTGS2CDK4CCND1 | |
| SCHEMBL14511797 | 0.83 | PTGS2 (0.43) | PTGS2 | |
| SCHEMBL14537817 | 0.82 | MAPT (0.38) | PTGS2PTGS1CDK4CCND1 | |
| SCHEMBL14511817 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1NR3C1 | |
| SCHEMBL14511815 | 0.81 | TSHR (0.43) | CDK4CCND1 | |
| SCHEMBL14512349 | 0.77 | ERN1 (0.52) | PTGS2PTGS1 | |
| SCHEMBL14537815 | 0.77 | CA12 (0.43) | PTGS2 | |
| SCHEMBL14511821 | 0.77 | CYP17A1 (0.45) | PTGS2NR3C1 | |
| SCHEMBL14511816 | 0.76 | PDGFRB (0.42) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |