Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511937 | 0.93 | TSHR (0.47) | ERN1ALDH1A1TSHRCTSVCTSL | |
| SCHEMBL14511950 | 0.91 | ERN1 (0.44) | ERN1PTGS2ALDH1A1TSHRKDM4E | |
| SCHEMBL14512358 | 0.90 | PTGS2 (0.43) | ERN1PTGS2PTGS1ALDH1A1LMNA | |
| SCHEMBL14512473 | 0.90 | ERN1 (0.59) | ERN1PTGS2PTGS1SLKALDH1A1 | |
| SCHEMBL14512474 | 0.90 | CTSV (0.47) | ERN1PTGS2PTGS1ALDH1A1CTSV | |
| SCHEMBL14511940 | 0.88 | MGAM (0.45) | ALDH1A1TSHRKDM4ELMNAHSD17B10 | |
| SCHEMBL14512242 | 0.88 | MGAM (0.54) | ERN1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL14512973 | 0.87 | MGAM (0.50) | ERN1PTGS2PTGS1SLKALDH1A1 | |
| SCHEMBL14511815 | 0.86 | TSHR (0.43) | ERN1ALDH1A1TSHRCTSVCTSL | |
| SCHEMBL14512394 | 0.85 | RXRA (0.56) | KDM4EHPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |