Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919386 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10969374 | 0.82 | KDM4E (0.34) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL5919287 | 0.81 | PTPRZ1 (0.49) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL17046666 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL2329595 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL699323 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL5687891 | 0.77 | KDM4E (0.31) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL698851 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1LMNA | |
| Water SCHEMBL28356277 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL518851 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| CN-117062607-A | Methyl substituted pyridine and pyridazine compounds, derivatives thereof and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-114907282-B | Method for synthesizing 4-phenyl alkenyl isoxazole derivative | 华南理工大学 | 2023-08-22 | — | — | CN | claimed |
| CN-114989079-B | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2023-06-23 | — | — | CN | claimed |
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | claimed |
| CN-112778125-B | Aryl phenol compound and synthesis method and application thereof | 华东师范大学 | 2023-02-17 | — | — | CN | claimed |
| CN-109705050-B | Method for synthesizing 4-sulfenyl isoxazole | 华南理工大学 | 2022-12-16 | — | — | CN | claimed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| CN-114989079-A | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114907282-A | Method for synthesizing 4-phenyl alkenyl isoxazole derivative | 华南理工大学 | 2022-08-16 | — | — | CN | claimed |
| WO-2001019796-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| US-4970328-A | MITICIDE, FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | claimed |
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-4944795-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | claimed |
| US-4929642-A | MITICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | claimed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0300218-A1 | Use of substituted 1,4-naphthoquinones against nites and fungi | BAYER AG (DE) | 1989-01-25 | — | — | EP | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| EP-0127062-A2 | Alkylene-bis-heterocyclyl biguanides | BAYER AG (DE) | 1984-12-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | UNG, TYMP, TYMS | ALDH1A1 170/4885KDM4E 1497/4885TDP1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.