Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145124 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1TDP1 | |
| SCHEMBL4615150 | 0.80 | SLC6A4 (0.41) | KDM4EAR | |
| SCHEMBL10969374 | 0.78 | KDM4E (0.34) | KDM4EALDH1A1TDP1 | |
| SCHEMBL17046666 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| SCHEMBL699323 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| SCHEMBL19622359 | 0.75 | MAPT (0.41) | KDM4EALDH1A1TDP1 | |
| SCHEMBL26669837 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1TDP1AR | |
| SCHEMBL25974578 | 0.73 | MLYCD (0.44) | KDM4EALDH1A1TDP1 | |
| SCHEMBL698851 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1TDP1 | |
| SCHEMBL5687891 | 0.73 | KDM4E (0.31) | KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812389-B1 | AZABICYCLOHEPTYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-08-17 | — | — | EP | disclosed |