SCHEMBL14513293

SCHEMBL14513293

Fc1ccc(C2=Nc3cc(-c4ncc[nH]4)ccc3Sc3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.46
CNR2 P34972 2/20 0.39
NISCH Q9Y2I1 2/20 0.38
MTOR P42345 1/20 0.38
ADK P55263 1/20 0.38
DRD2 P14416 2/20 0.36
OPRK1 P41145 1/20 0.34
VCP P55072 1/20 0.34
CASP6 P55212 1/20 0.33
SCN9A Q15858 1/20 0.33
ELOVL6 Q9H5J4 1/20 0.32
PLEC Q15149 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5064580 0.89 CNR1 (0.53) CNR1CNR2NISCHMTORADK
SCHEMBL14206968 0.85 CNR1 (0.40) CNR1CNR2NISCHMTORADK
SCHEMBL14043756 0.76 PLEC (0.42) CNR1NISCHMTORADKPLEC
SCHEMBL2049365 0.72 NISCH (0.52) NISCHMTORADKCASP6
SCHEMBL13808032 0.70 CNR1 (0.72) CNR1CNR2
SCHEMBL14206110 0.70 CNR1 (0.53) CNR1CNR2DRD2PLEC
SCHEMBL13808030 0.70 CNR1 (0.65) CNR1CNR2PLEC
SCHEMBL13807927 0.69 CNR1 (0.57) CNR1CNR2PLEC
SCHEMBL14043755 0.69 CNR1 (0.50) CNR1CNR2DRD2PLEC
SCHEMBL771236 0.68 NISCH (0.64) NISCHMTORADKOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070105819-A1 CB-1 modulating compounds and their use ACADIA PHARMACEUTICALS, INC. 2007-05-10 US disclosed
US-20070105819-A1 CB-1 modulating compounds and their use ACADIA PHARMACEUTICALS, INC. 2007-05-10 US disclosed
WO-2007047737-A1 CB-1 MODULATING COMPOUNDS AND THEIR USE ACADIA PHARMACEUTICALS INC. (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105819-A1 CB-1 modulating compounds and their use CNR1, CNR2, FAAH CNR1 1/4885CNR2 2/4885NISCH 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.