Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5235535 | 0.85 | TACR1 (0.38) | TACR1GPBAR1 | |
| SCHEMBL14514048 | 0.71 | TACR1 (0.44) | TACR1GPBAR1 | |
| SCHEMBL5227594 | 0.70 | CACNA1H (0.37) | TACR1GPBAR1 | |
| SCHEMBL5228959 | 0.67 | CACNA1H (0.38) | TACR1GPBAR1 | |
| SCHEMBL5528489 | 0.62 | GPBAR1 (0.42) | TACR1GPBAR1 | |
| SCHEMBL7522146 | 0.61 | TACR1 (0.60) | TACR1GPBAR1 | |
| SCHEMBL13891736 | 0.61 | RAF1 (0.43) | TACR1 | |
| SCHEMBL14433651 | 0.60 | PPARG (0.44) | — | |
| SCHEMBL6991745 | 0.60 | TACR1 (0.57) | TACR1GPBAR1 | |
| SCHEMBL19285672 | 0.60 | CES2 (0.50) | TACR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496059-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2007-08-15 | — | — | EP | disclosed |