Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 12/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719270 | 0.95 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL14514535 | 0.94 | KCNH2 (0.85) | CCR5KCNH2 | |
| SCHEMBL13719039 | 0.94 | CCR5 (0.90) | CCR5KCNH2 | |
| SCHEMBL3070606 | 0.94 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL3070604 | 0.94 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL14514556 | 0.91 | KCNH2 (0.88) | CCR5KCNH2 | |
| SCHEMBL30227220 | 0.90 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL1080663 | 0.90 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL1198749 | 0.90 | KCNH2 (1.00) | CCR5KCNH2 | |
| SCHEMBL13719436 | 0.90 | KCNH2 (0.86) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217721-B2 | Tropane derivatives useful in therapy | PFIZER, INC. (US) | 2007-05-15 | — | — | US | disclosed |