SCHEMBL14515907

SCHEMBL14515907

CC(C)(C)c1ccc(N(c2ccc(C(C)(C)C)cc2)c2ccc3cc4cc(N(c5ccc(C(C)(C)C)cc5)c5ccc(C(C)(C)C)cc5)ccc4cc3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.37
TYR P14679 1/20 0.37
ALDH1A1 P00352 5/20 0.34
RAB9A P51151 3/20 0.34
HPGD P15428 2/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
TERT O14746 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17430702 0.89 TSHR (0.56) TSHRLMNATYRALDH1A1RAB9A
SCHEMBL5074296 0.88 ALDH1A1 (0.40) TSHRLMNATYRALDH1A1RAB9A
SCHEMBL19774843 0.87 TSHR (0.48) TSHRLMNATYRRAB9ANPC1
SCHEMBL21004684 0.85 CYP2A6 (0.39) TSHRLMNATYRALDH1A1RAB9A
SCHEMBL14515929 0.84 MEN1 (0.37) ALDH1A1RAB9AMEN1KMT2ANPSR1
SCHEMBL13304340 0.84 TSHR (0.38) TSHRLMNATYRALDH1A1RAB9A
SCHEMBL16344415 0.84 KIF11 (0.39) ALDH1A1RAB9ANPC1MEN1KMT2A
SCHEMBL21870184 0.84 DYRK1A (0.33) RAB9ANPC1MAPTMEN1KMT2A
SCHEMBL21870452 0.84 DYRK1A (0.33) RAB9ANPC1MAPTMEN1KMT2A
SCHEMBL13380680 0.83 CYP1A2 (0.41) ALDH1A1MAPTAPPCYP1A2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
EP-1775334-A1 Organic electroluminescence device LG Electronics Inc. (KR) 2007-04-18 EP disclosed