Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995385 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL7904262 | 0.82 | ALDH1A1 (0.70) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL13995392 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL13176134 | 0.80 | LMNA (0.68) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL18506963 | 0.78 | POLB (0.68) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL12793245 | 0.78 | POLB (0.88) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL18184510 | 0.77 | POLB (0.69) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL13995367 | 0.77 | LMNA (0.64) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL23283615 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAPOLBKDM4E | |
| SCHEMBL12015807 | 0.76 | POLB (0.67) | ALDH1A1LMNAGAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007065683-A1 | ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |