Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581668 | 0.81 | MEN1 (0.71) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27886023 | 0.81 | MEN1 (0.71) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12282111 | 0.78 | MEN1 (0.76) | MEN1KMT2AUSP2NAMPTALDH1A1 | |
| SCHEMBL10851211 | 0.78 | MEN1 (0.76) | MEN1KMT2AUSP2NAMPTALDH1A1 | |
| SCHEMBL2241959 | 0.78 | ALDH1A1 (0.67) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3770117 | 0.77 | KDM4E (0.54) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4072272 | 0.77 | MEN1 (0.84) | MEN1KMT2AUSP2NAMPTALDH1A1 | |
| SCHEMBL12286004 | 0.76 | GAA (0.50) | USP2NAMPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1193355 | 0.75 | ALDH1A1 (0.63) | MEN1KMT2AUSP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28811687 | 0.75 | ALDH1A1 (0.63) | MEN1KMT2AUSP2NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070398-A1 | POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS | SCHERING CORPORATION (US) | 2007-06-21 | — | — | WO | disclosed |