Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282111 | 0.85 | MEN1 (0.76) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4072272 | 0.84 | MEN1 (0.84) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9581668 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27886023 | 0.82 | MEN1 (0.71) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13936597 | 0.81 | MEN1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11790805 | 0.80 | KMT2A (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2241959 | 0.79 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14516232 | 0.78 | MEN1 (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1193355 | 0.76 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11543936 | 0.76 | QDPR (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617309-A | Sulfur-containing indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0105397-A1 | Sulphuric indole derivatives | MERCK PATENT GmbH (DE) | 1984-04-18 | — | — | EP | disclosed |